Blocks HMGCRDisrupting critical cellular functions in cancer, i.e., membrane integrity, cell cycle progression, and signal transduction.Induces apoptosis and autophagy.Causes cell cycle arrest at the G1Inhibits adhesion, migration, invasion, and angiogenesis.Downregulates VEGF and MMP9 to prevent metastasis and tumor vascularization.Affects multiple signaling pathways, including AKT/mTOR, MAPK, and Myc. The gene discussed is MMP9; the disease is cancer.