This could indicate a potential confounding effect by unnoticed infections that may have evoked particularly strong cellular immune responses in the Tut group, thereby contributing to the lower failure rate observed for CD4+ and CD8+ responses (Figure 2B; pre-3 and post-3 heatmaps mark M/N reactivity as black circles and PCR-confirmed infections as “P” beside the tumor type-encoding colored dot). Here, CD8A is linked to infection.