We observed that elevated inflammatory levels—including WBC (<4,800 or >10,800 per mm3), IL-6 (>150 pg/ml), procalcitonin (>0.1 ng/ml), and C-reactive protein (>10 mg/l)—were significantly associated with a higher rate of in-hospital mortality after controlling for age, Black, White, Asian, Latino, temperature, mean arterial pressure, and oxygen saturation in all patients (CHF and non-CHF), as shown in the adjusted II model. This evidence concerns the gene CRP and congestive heart failure.