The therapeutic potential of NGF has also been tested in neurotrophic keratitis (Bonini et al., 2000), glaucoma (Lambiase et al., 2009a), macular degeneration (Lambiase et al., 2009b), retinitis pigmentosa (Falsini et al., 2016), and pressure ulcers (Bernabei et al., 1999; Landi et al., 2003). This evidence concerns the gene NGF and decubitus ulcer.