Notably, IL-6 inhibition has shown benefit in other inflammatory conditions with serositis, such as adult-onset Still’s disease and systemic juvenile arthritis.15–18 Case reports have also described improvement in rheumatologic-associated pericarditis with tocilizumab.17,18 Our case adds novel evidence in idiopathic recurrent pericarditis. The gene discussed is IL6; the disease is pericarditis.