In colon carcinoma, CX3CL1 has been associated with immune response evasion 12, while in lung cancer, there is evidence that CX3CL1 has a dual role, on the one hand favoring the antitumor response through the recruitment of various effector cells 13, and on the other hand, its presence has been related to metastasis and, therefore, with disease progression. This evidence concerns the gene CX3CL1 and lung cancer.