AKT1 and neoplasm: The mechanism of action for R. tripartite extractions is thoroughly explained by Tlili et al., 2021, which involves the inhibition of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT mammalian target of rapamycin (mTOR) pathway that eventually results in the induction of apoptosis and the suppression of tumor growth, as shown previously in Figure 4, 70.