For example, deletion of BRCA1 (HGNC: 1100) exon 86 and CHEK2 (HGNC: 16627) exons 9-109 have been associated with breast cancer predisposition (OMIM 604370, 609265), and BRCA1 full-gene deletion has been described in 2 Spanish families with hereditary breast and ovarian cancer.10 Here, BRCA1 is linked to ovarian cancer.