EIF4E1B and glioblastoma: Conversely elevated EIF4E1B after NDs treatment was found to have a negative correlation with other m7G methylation regulators and was designated as a favorable prognostic factor for glioblastoma patients.101 Proteins involved in RNA transport and stability, translation, splicing regulation, and miRNA sorting into extracellular vesicles are considered novel but attractive molecular markers or potential therapeutic targets.87,102 Nevertheless, their role in tumors can drastically vary and needs further investigation, especially in highly heterogenous tumors, like glioblastoma.