STAG1 and microcephaly: The study by Lehalle et al. suggested that there was no notable disparity in clinical manifestations caused by STAG1 deletions or STAG1 variants apart from microcephaly (4/7 cases with SVs of STAG1 had microcephaly, whereas 10 cases with STAG1 SNVs/indels didn't have microcephaly) (1).