In 2015, it was reported that lipid metabolite commendamide (N-acyl 3-hydroxy-palmitoyl glycine) is an agonist of the host G-protein coupled receptor (GPCR) GPR132/G2A [16], which plays key roles in monocyte chemotaxis and macrophage function contributing to atherosclerosis [17,18]. This evidence concerns the gene GPR132 and atherosclerosis.