An imbalanced Treg/Th17 ratio has been previously associated with inflammatorycardiovascular diseases such as atherosclerosis and viral myocarditis [26, 27].Treg cells typically exert protective effects by suppressing immune activationthrough IL-10 secretion, whereas Th17 cells promote inflammation and tissueinjury [28, 29]. The gene discussed is IL10; the disease is viral myocarditis.