EGFR and Menkes disease: Few studies have described the association: Transforming growth factor alpha (TGF-α) which is elevated in pediatric MD binds to epidermal growth factor receptor (EGFR) on the mucosa of the stomach, leading to foveolar hyperplasia, hypertrophy in the body and fundus, decrease in acidic secretion, proliferation of mucus-secreting cells, and increase in probability of neoplastic transformation [10].