(36) confirmed that in the mouse sepsis model established by cecal ligation and puncture, the expression levels of Fas, caspase-3, caspase-8, and caspase-9 were significantly upregulated, while the expression levels of CD4+/CD8+ T lymphocytes and CD19+ B lymphocytes were significantly downregulated. The gene discussed is CASP3; the disease is Sepsis.