To investigate potential molecular subtypes in HCC, consensus clustering was performed based on the expression profiles of nine hub genes (FCGR2A, ITGB2, CD86, CYBB, FCGR1A, HCK, MNDA, PLEK, and CCR1) using the Consensus ClusterPlus package. The gene discussed is ITGB2; the disease is hepatocellular carcinoma.