Compared with those of the BD+ETEC group, the mRNA expression levels of MyD88, NF-κB, IKKα, IKKβ (P < 0.01), TLR4, NLRP3, and caspase-1 (P < 0.05) were decreased, whereas the level of IκBα was increased (P < 0.01) in the LN+ETEC group (Figure 3E). This evidence concerns the gene CASP1 and Behcet disease.