Compared with those of the BD+NB group, the mRNA expression levels of TLR4, MyD88, NF-κB, NLRP3, IKKα, and caspase-1 were significantly decreased (P < 0.05), whereas the level of IκBα was increased (P < 0.01) in the LN+NB group. Here, CHUK is linked to Behcet disease.