Emerging evidence underscores the pivotal role of interleukins (ILs) in pancreatitis pathogenesis across the disease spectrum, encompassing both pro-inflammatory mediators (e.g., IL-1β, IL-6, and IL-8) and anti-inflammatory regulators (e.g., IL-10 and IL-37) 24-26. The gene discussed is IL10; the disease is pancreatitis.