METTL14 and hepatocellular carcinoma: Notably, traditional Chinese medicines show unique advantages: Resina Draconis extract induces HCC cell apoptosis by downregulating Mettl3182; Ling Gui Zhu Gan soup reduces liver fat degeneration by decreasing m6A methylation and Socs2 expression183; Gan Jiang Ling Zhu soup promotes Mettl14 and Ugt2a3 expression to alleviate NASH184; indole-3-lactic acid regulates Cyp8b1 via Fto/m6A/Ythdf2 to inhibit liver fat accumulation185; and cucurbitacin B covalently binds to Igf2bp1 to block m6A-modified mRNA recognition, offering new directions for liver cancer drug development186.