Wtap-mediated m6A modification stabilizes lnc-OXAR via Igf2bp2, leading to oxaliplatin resistance in NASH-related HCC164, promotes HCC progression via the HuR-est1-p21/p27 axis165 and upregulates the expression of autophagy-related 5 (Atg5), promoting its translation during ferroptosis. The gene discussed is ATG5; the disease is metabolic dysfunction-associated steatohepatitis.