In contrast, the addition of 2,3 cGAMP reversed the inhibitory effects of MS on microglia (p-P65, P = 0.0497; p-IRF3, P = 0.0277; cGAS, P = 0.0455; STING, P = 0.0301; Fig. 7B-C). This evidence concerns the gene IRF3 and myeloid sarcoma.