Studies have reported that venom extracts from certain scorpions can restore serum levels of serum ALP, TRAP, PTH, osteocalcin, TNF-α, and bone minerals in OVX rats, combatting osteoporosis and enhancing BMD (Gomes et al., 2009; Haldar et al., 2010; Uzair et al., 2018). The gene discussed is TNF; the disease is osteoporosis.