TCGA categorized GC into Epstein–Barr virus (EBV) associated, microsatellite instable (MSI), genomically stable (GS), and chromosomal instability (CIN) subtypes, while the ACRG classified GC into microsatellite stable (MSS)/epithelial–mesenchymal transition (EMT), MSI, MSS/p53 +, and MSS/p53− subtypes (Puliga et al. 2021). The gene discussed is TP53; the disease is gastric cancer.