CRP and alkaline phosphatase measurement: analysed thirty clinical and laboratory variables, fifteen of which were identified as significant predictors of AP progression: (WBC, fibrinogen (FIB), alanine aminotransferase (ALT), alkaline phosphatase (ALP), ALP-to-hemoglobin ratio (ALP/Hb), LDH, LDH-to-hemoglobin ratio (LDH/Hb), urea, creatinine, CRP, PCT, blood glucose, and the Acute Physiology and Chronic Health Evaluation – II (APACHE-II), Bedside Index for Severity in AP (BISAP), and Sequential Organ Failure Assessment scores (SOFA).