Activating the PBN (CGRP) → BNST circuit (Chen et al. 2018; Bowen et al. 2020) or CGRP infusions in the BNST (Sink et al. 2011; Sink et al. 2013) induce anxiety‐like behavior and physiological responses (Bowen et al. 2020), whereas inhibition decreases anxiety‐like behavior (Sink et al. 2011; Sink et al. 2013). This evidence concerns the gene CALCA and Anxiety.