NEFL and Alzheimer disease: In AD, baseline NfL was strongly predictive in the short term but progressively attenuated, with HRs of 4.02 (95% CI, 3.08–5.24) at 2 years, 2.18 (95% CI, 1.90–2.50) at 5 years, and 1.37 (95% CI, 1.27–1.48) at 10 years.