This aligns with the requirement of Slc7a7 for efferocytosis and the maintenance of an anti-inflammatory state in macrophages,60,61 as well as findings from patients with SLC7A7 mutations, which results in altered inflammatory responses and impaired phagocytosis by macrophages.76,77 While our findings highlight the importance of Slc7a7, further research should include other ubiquitously expressed glutamine transporters to fully understand the role of glutamine metabolism in atherosclerosis. Here, SLC7A7 is linked to atherosclerosis.