The SYCE1 gene encodes synaptonemal complex central element protein 1 (<−1.7-fold) and SYCE1L (<−1.6-fold), which are expressed in the synaptonemal complex of meiotic chromosomes and whose deficiency is linked to infertility in mice,57 both downregulated in LCFs (Figure 6I). The gene discussed is SYCE1L; the disease is Infertility.