CRP and metabolic dysfunction-associated steatotic liver disease: In a study of 6558 participants, the hs-CRP level was elevated in NAFLD and was independently associated after adjustment.[33] As reported by Cui et al, CRP has been shown to have a significant mediating role in the association between the triglyceride glucose index and cardiovascular events.[34] Pursuing a regular physical exercise regimen, implementing dietary modifications, maintaining an optimal weight, and employing judicious pharmacological therapies to mitigate IR and inflammation may reduce the development of NAFLD.