The mTOR inhibitor everolimus can reduce the oxidative stress caused by HP, significantly reduce the expression of pro-inflammatory cytokines, and thus protect gastric epithelial cells.[42] The AR has recently been shown to play a role in the prevention of gastric metaplasia by inhibiting the activation of group 2 congenital lymphocytes.[43] Moreover, MAPK14 is a member of the MAPK family that functions by regulating various physiological and pathological processes in cells, including cell growth and differentiation, adaptation to environmental stress, and the inflammatory response. The gene discussed is MAPK14; the disease is Gastric Metaplasia.