At the end of this study, compared with those in the control group, the curative effect on angina pectoris; the total nitroglycerin discontinuation rate; the total TCM syndrome score; and the scores of several dimensions of the SAQ, B-type natriuretic peptide precursor (NT-proBNP), asymmetric dimethylarginine, endothelial nitric oxide synthase, nitric oxide (NO) and endothelin 1 in CHGZ group were significantly greater (P < .05 or P < .01). This evidence concerns the gene EDN1 and angina pectoris.