CERS6 and esophageal squamous cell carcinoma: We investigated whether CERS6 expression was associated with the prognosis of ESCC by the log-rank test and found that patients with high CERS6 expression had significantly shorter overall survival than those with low CERS6 expression (P < 0.05, Fig. 1E) (median survival time was 48 and 61 months, respectively).