As shown in Figure 5A,B, the protein levels of CypA and SLC7A11 were upregulated in chemoresistant NSCLC cell lines (A549/DDP, A549/DTX, H1299/DDP, H1299/DTX) compared to that in parental cells (A549, H1299). This evidence concerns the gene SLC7A11 and non-small cell lung carcinoma.