GPX4 and cancer: Ferroptosis, an iron‐dependent, lipid peroxidation‐driven form of regulated cell death, has emerged as a pivotal player in cancer biology, particularly in the context of tumor resistance to therapy.[9] The evasion of ferroptosis in drug‐resistant tumors often involves upregulation of antioxidant defenses, most notably the SLC7A11/glutathione (GSH)/glutathione peroxidase 4 (GPX4) axis.