In line with the results obtained using C. elegans AD-like models, NMN improved recognition memory in the AAV-mediated hTau.P301S mice to the control level as assessed by NOR test, and Eva1c overexpression partly mimic the effect of NMN treatment, possibly due to a big variation in the performance of the animals (Fig. 6B). The gene discussed is NTS; the disease is Alzheimer disease.