LRIG1 and central nervous system cancer: Thus, low grade glioma showed significantly higher LRIG1 level than high grade (WB: 0.215 ± 0.126 vs. 0.079 ± 0.052; p = 0.0118, Figure 1E; qPCR: 2.868 ± 1.862 vs. 0.802 ± 0.503, p < 0.0001, Figure 1J), which was also visualized in immunofluorescence staining (Figure 3A).