When comparing primary and secondary GBM, we found significantly higher LRIG1 expression in secondary compared to primary GBM (WB: 0.083 ± 0.038 vs. 0.052 ± 0.028, p = 0.014, Figure 2A, qPCR: 0.953 ± 0.645 vs. 0.631 ± 0.382, p = 0.0326, Figure 2D; Immuno: Figure 3B). Here, LRIG1 is linked to glioblastoma.