Witzens-Harig, M. et al. Their results revealed that ATLL cells are highly susceptible to Navitoclax-induced apoptosis, mainly due to elevated expression of the pro-apoptotic protein BAX, which sensitizes these cells to mitochondrial-mediated cell death upon BCL-2 inhibition [59]. Here, BCL2 is linked to adult T-cell leukemia/lymphoma.