Fabry disease (FD; OMIM#301500) is an X‐linked lysosomal storage disorder caused by pathogenic GLA variants, leading to alpha‐galactosidase A deficiency with sphingolipid accumulation, particularly globotriaosylceramide (Gb3) and globotriaosylsphingosine (lyso‐Gb3) [1], with multiorgan dysfunction, especially cardiac and renal. The gene discussed is GLA; the disease is Fabry disease.