CD274 and laryngotracheoesophageal cleft: Through the synergistic effect of PTT and dual PD‐L1/VEGF blockade, GSBVVP remodeled the immunosuppressive TME, reversed T‐cell exhaustion and angiogenic signaling pathways, thereby suppressing the growth, metastasis, and recurrence of LC, and providing long‐term antitumor protection via the induction of immune memory responses.[402] The combined use of PTT and ICB shows strong therapeutic potential.