RHOA and cancer: We became interested in ARHGAP29, a putative RhoA GAP that is upregulated in many migratory cancer types and has variants that cause cleft palate (Shimizu et al., 2020; Ripperger et al., 2007; Meng et al., 2018; Kolb et al., 2020; Jiang et al., 2023; Paul et al., 2017; Liu et al., 2017; Leslie et al., 2012).