Branch‐specific analysis comparing ND group‐dominant branches (States 1, 3, 4) and HFD/HCC‐dominant branches (States 1, 3, 5, 6 and 1, 3, 5, 7) revealed upregulation of pathogenicity‐related genes—including CD29—in pathological branches (Figure 5I). This evidence concerns the gene ITGB1 and hepatocellular carcinoma.