ITGB1 and hepatocellular carcinoma: Immunohistochemistry of liver tissues from MASLD model mice showed that, compared with the ND group, CD29 and FOXP3 were concurrently upregulated in the HFD and HCC groups, accompanied by enhanced EMT markers, with no significant differences observed between the HFD and HCC groups (p < 0.001, Figure 7C,D).