MYC and acute lymphoblastic leukemia: The FAB scheme designated Burkitt-type acute lymphoblastic leukemia as “L3 ALL.” In current WHO/ICC classifications, this is no longer viewed as a subtype of ALL it is recognized asBurkitt Lymphoma/Leukemia, a mature B-cell neoplasm with a characteristic MYC translocation.17 In other words, cases that would previously be called L3 ALL are now classified and treated asBurkitt lymphoma, reflecting their mature B-cell origin.