According to the serological grouping of MG patients, those with single-positive AChR-Ab, MuSK-Ab, and LRP4-Ab were defined as AChR-MG, MuSK-MG, and LRP4-MG, respectively, and ALDOA-Ab positivity was observed in 30 out of 613 AChR-MG patients, with a positivity rate of 4.89%. The gene discussed is MUSK; the disease is myasthenia gravis.