The present study compares the serum levels of selected cytokines and chemokines—IL-17, IL-22, IL-23, IL-8, IL-21, CCL20, CXCL10, CCL2and CCL5—in schizophrenia patients to healthy controls due to growing evidence linking immune-inflammatory and metabolic dysregulation to schizophrenia. This evidence concerns the gene CXCL8 and schizophrenia.