Consistent with these in vitro findings, analysis of xenograft tumor tissues revealed a similar downregulation of COX2, iNOS, Vimentin, and Slug, together with an upregulation of Bax and suppression of Bcl2, further supporting the induction of mitochondria‐mediated apoptosis by FPHPE (Figure 6C). This evidence concerns the gene SNAI2 and neoplasm.