Furthermore, HuR can bind to and stabilize multiple cyclin mRNAs, such as Cyclin A2, Cyclin B1 (106, 110), Cyclin D1 (111), and Cyclin E1 (76), which promote the transition from G1 to S phase and accelerate cell cycle progression in CRC cells (106). The gene discussed is ELAVL1; the disease is colorectal carcinoma.