Our transcriptomic validation using the GSE213346 dataset confirmed increased expression of TLS-related genes (IRF4, TNFRSF17) and B/plasma cell markers (CD79A/B, CD19, MZB1, CD38) in erosive and recurrent OLP, further linking humoral activation to poor clinical outcomes. The gene discussed is TNFRSF17; the disease is oral lichen planus.