For example, the chemokine CXCL10 promotes the infiltration of T cells into the tumor microenvironment, enhancing anti-tumor immunity, while CCL20 recruits Tregs via the FOXO1/CEBPB/NF-κB signaling pathway, thereby promoting chemotherapy resistance in colorectal cancer (91, 92). Here, NFKB1 is linked to neoplasm.