For example, the chemokine CXCL10 promotes the infiltration of T cells into the tumor microenvironment, enhancing anti-tumor immunity, while CCL20 recruits Tregs via the FOXO1/CEBPB/NF-κB signaling pathway, thereby promoting chemotherapy resistance in colorectal cancer (91, 92). The gene discussed is FOXO1; the disease is neoplasm.