Chord mapping revealed core genes (e.g., NDUFB6, RPL15, ATP5PB) involved in multiple interconnected pathways (Figure 2C).DO analysis confirmed enrichment in cardiomyopathy, coronary artery disease, and myocardial infarction, supporting the cardiovascular specificity of the identified genes (Figure 2D). Here, NDUFB6 is linked to myocardial infarction.