Emerging evidence suggests UVB therapy can target and inhibit cell apoptosis while simultaneously suppressing the secretion of inflammatory factors including IL-18, IL-6, TNF-α, and IL-1R, thereby demonstrating therapeutic efficacy in the management of inflammatory dermatological conditions such as atopic dermatitis and psoriasis (17, 18, 34, 40), suggesting its potential therapeutic effects through modulation of both apoptotic and pyroptotic pathways. Here, IL1R1 is linked to atopic eczema.