Subsequently, both short-term and long-term cytotoxicity assays against U87-luc and 786-0-luc cells were performed and the results demonstrated that with the existence of AZD1208, the impaired short-term (Figure S3F) and long-term (Figure S3G-H) tumor-killing capabilities of anti-CD70 CAR-T cells after hypoxia treatment were restored. Here, CD70 is linked to neoplasm.