A comparison of the maternal T1D-associated loci with differential blood methylation and transcription in much older offspring of mothers with T1D24 revealed no overlapping CpG site or DMR, but some similar gene targets, including Potassium voltage-gated channel subfamily Q member 2 (KCNQ2) on chromosome 20q13.33, Caldesmon 1 (CALD1) on chromosome 7q33 and Chitinase domain containing 1 (CHID1) on chromosome 11p15.5. This evidence concerns the gene CALD1 and type 1 diabetes mellitus.