The gene ontologies of these eQTM-derived genes indicated over-representation for 20 terms (Fisher’s exact test, PFDR < 0.05; Fig. 4a), including eight that are directly related to immune system function, particularly peptide processing in MHC human leukocyte antigen (HLA) class I, which is relevant to T1D susceptibility31. The gene discussed is HLA-C; the disease is type 1 diabetes mellitus.