HOXA5 and type 1 diabetes mellitus: Beyond HOXA5, a major CpG target in our analysis with significant roles in chronic inflammation22,23, we discovered that HOX antisense intergenic RNA myeloid 1 (HOTAIRM1), a long non-coding RNA, was a particular target of the differentially methylated CpGs in the offspring of mothers with T1D, especially in the eQTM data.