Moreno et al. reported that heme levels and export were significantly increased in adipose tissue in T2DM patients and that the gene level of heme exporter (FLVCR1) was positively correlated with fasting blood glucose, suggesting that systemic glucose impairment during T2DM may be associated with heme export from adipose tissue [57]. This evidence concerns the gene FLVCR1 and type 2 diabetes mellitus.